Kumayambiriro kwa chaka cha 2025, ofufuza ochokera ku yunivesite ya Washington ndi Brigham ndi Women's Hospital (chipatala chophunzitsira cha Harvard Medical School) adawulula njira zomwe sizinachitikepo zochizira matenda a Alzheimer's - kupuma movutikira.xenonmpweya, umene osati linalake ndipo tikulephera neuroinflammation ndi amachepetsa ubongo atrophy, komanso kumawonjezera chitetezo minyewa limati.

Xenonndi Neuroprotection

Matenda a Alzheimer's ndi matenda ofala kwambiri a neurodegenerative mwa anthu, ndipo chifukwa chake akukhulupirira kuti amagwirizana ndi kuchuluka kwa mapuloteni a tau ndi mapuloteni a beta-amyloid muubongo. Ngakhale kuti pakhala pali mankhwala amene amayesa kuchotsa mapuloteni oopsawa, sanathandize kuchepetsa kufalikira kwa matendawa. Choncho, sitikumvetsa bwinobwino chomwe chimayambitsa matendawa komanso mankhwala ake.

Kafukufuku wasonyeza kuti pokoka mpweyaxenonakhoza kuwoloka chotchinga magazi-ubongo ndi bwino kwambiri udindo wa mbewa ndi zitsanzo matenda Alzheimers pansi zasayansi mikhalidwe.Kuyeserako kunagawidwa m'magulu awiri, gulu limodzi la mbewa limasonyeza tau mapuloteni ndipo gulu lina linali ndi mapuloteni a beta-amyloid. Zotsatira zoyesera zidawonetsa kuti xenon sanangopangitsa mbewa kukhala zogwira ntchito, komanso kulimbikitsa chitetezo cha microglia, chomwe chili chofunikira pakuchotsa mapuloteni a tau ndi beta-amyloid.

Kutulukira kwatsopano kumeneku ndi kwachilendo kwambiri, kusonyeza kuti zotsatira za neuroprotective zitha kupangidwa pokoka mpweya wa inert. Cholepheretsa chachikulu pankhani ya kafukufuku ndi chithandizo cha Alzheimer's ndikuti ndizovuta kwambiri kupanga mankhwala omwe amatha kudutsa chotchinga chamagazi ndi ubongo, komansoxenonakhoza kuchita izi.

Ntchito zina zamankhwala za xenon

1. Anesthesia ndi analgesia: Monga mpweya wabwino wogonetsa,xenonamagwiritsidwa ntchito kwambiri chifukwa cha kulowetsedwa mofulumira ndi kuchira, kukhazikika kwa mtima wamtima komanso chiopsezo chochepa cha zotsatira zake;

2. Zotsatira za Neuroprotective: Kuwonjezera pa zomwe zingatheke kuchiritsa matenda a Alzheimer omwe tawatchula pamwambapa, xenon adaphunziranso kuti achepetse kuwonongeka kwa ubongo chifukwa cha neonatal hypoxic-ischemic encephalopathy (HIE);

3. Kuika chiwalo ndi chitetezo:Xenonzingathandize kuteteza ziwalo zoperekera kuvulala kwa ischemia-reperfusion, zomwe ndizofunikira kwambiri pakuwongolera bwino kwa kuyika;

4. Kulimbikitsa Radiotherapy: Kafukufuku wina woyambirira wasonyeza kuti xenon ikhoza kupititsa patsogolo kukhudzidwa kwa zotupa ku radiotherapy, zomwe zimapereka njira yatsopano yothandizira khansa;